November 3rd, 2025
HBOT for Post-Surgical Healing

Accelerate Wound & Surgical Healing with Hyperbaric Oxygen Therapy (HBOT)
Some wounds take longer to heal than they should, and surgery itself puts tissue under strain. Hyperbaric Oxygen Therapy (HBOT) supports tissue repair by raising the amount of oxygen your blood can deliver to healing tissue.
HBOT is increasingly recognised as an adjunct treatment for accelerating healing post-surgery or in challenging wound cases. You breathe 100% oxygen under increased pressure (typically 2-3 atmospheres absolute, ATA), so your blood carries far more dissolved oxygen. That oxygen fuels reparative processes: reducing inflammation, promoting new blood-vessel formation (angiogenesis), encouraging collagen synthesis and supporting tissue regeneration.
Clinically it is used for stalled wounds, post-surgical recovery, grafts and flaps, and burn or radiation injury.
Key Applications of HBOT in Healing & Recovery
Non-healing / slow-healing wounds
Ulcers and wounds that have stalled often suffer from hypoxia (insufficient oxygen). HBOT improves oxygen delivery, supports fibroblast and endothelial cell activity, and may accelerate closure of difficult wounds. A meta-analysis found HBOT significantly improved healing of diabetic lower-limb ulcers and reduced major amputations (RR ~0.54) in certain patients.
Post-surgical recovery, flaps and grafts
Surgery often disrupts circulation and places pressure on tissues. In one study, adjunctive HBOT improved outcomes in complicated acute wounds, flaps and grafts. HBOT enhances graft and flap survival, improves reperfusion injury outcomes and accelerates tissue repair.
Traumatic wounds, burns and radiation-induced injury
In cases of crush injury, compartment syndrome, thermal burns or radiation damage, HBOT supports healing by improving oxygenation, reducing oedema, mitigating reperfusion injury and enhancing microvascular recovery.
How HBOT Works: The Cellular & Physiological Mechanisms
1. Increases tissue oxygenation: by elevating ambient pressure and providing 100% oxygen, HBOT boosts the amount of oxygen dissolved in plasma, enabling oxygen delivery into poorly perfused tissues. This supports healing in zones where standard perfusion is compromised.
2. Stimulates angiogenesis & collagen synthesis: oxygen-rich environments promote growth factor expression, endothelial progenitor cell mobilisation, and collagen formation, all key to restoring structural integrity in damaged tissue.
3. Reduces inflammation & supports immune function: HBOT can reduce pro-inflammatory cytokines, support neutrophil and macrophage activity, and improve micro-circulatory function, assisting in both healing and infection resistance.
4. Mitigates reperfusion and hypoxic injury: after surgery or trauma, tissues may suffer from reduced blood flow or oxygen deprivation. HBOT helps restore function and limit secondary damage from hypoxia.
Our Approach
At Expand Health, HBOT sits inside a personalised, wellness protocol designed to support recovery and optimise longevity.
- For wound care in particular, each client is encouraged to do an initial consultation with our integrative medical doctor, who will assess wound status, surgical history, and recovery goals.
- Our health consultant or therapist will then tailor the number of sessions, the session pressure and the length to your healing.
- HBOT is paired with complementary therapies: advanced nutrition (to support collagen, micronutrients & repair), other modalities such as PEMF, red light therapy and compression/lymphoedema support when necessary, boosting the effect of the hyperbaric oxygen therapy.
- The clinic environment is quiet, so you can rest during a session.
What This Could Mean for You
- If you are recovering from surgery, especially reconstructive, orthopaedic or cosmetic surgery, and want to optimise healing, HBOT is a scientifically backed adjunct.
- If you have a wound that has stalled (diabetic, vascular, flap/graft site), adjunctive HBOT may significantly increase your healing odds and reduce risks of complications.
- If your goal is broader than closing the wound, HBOT can be built into the wider rehabilitation plan.
Planning the Sessions
At Expand Health, sessions are planned around your wound status, surgical history and recovery goals, with a team of practitioners behind the protocol.
If you'd like to explore whether HBOT may be right for your recovery and longevity plan, contact our team in Cape Town for a consultation.